Hi BrentW,
My guess is that you are pumping grease into a spindle housing with sealed bearings. It is a cruel engineering joke for many of the parts manufacturers to install fittings that do no good to grease.
Take one of your old spindles apart and wipe all the excess grease off and then look at the top and bottom bearings. They will likely have seals on both the inside and outside portion of the bearings. That means they are "sealed" bearings.
What many folks do (that now know this) is remove the inner seal (only) so when the spindle is greased at the fitting on the side of the housing, the grease can actually make it to the bearing rollers where it is needed.
Hope this helps you.